10. Use poor spelling or poor grammar _ This one should be pretty obvious. Academics on admissions committees are generally high achievers with high standards who won't disregard even simple typos. If your personal statement is not technically perfect, it can make you seem sloppy, lazy, or inattentive, which are not qualities anyone wants in a future colleague. Remember that the people skimming your essay are seeking a reason to reject your application and make the pile of possible admits smaller. Always get someone with strong writing skills to review your essay.
Just as a strong personal statement can get you in, a poor personal statement/essay can quickly eliminate you from the mix. When a medical school committee has a few hundred applicants, seeing typos, spelling mistakes or bad content will quickly move you to the bottom of the pile. The personal statement is a quick way to "weed out" similar applicants. With two similar applications, the personal statement can decide who gets an interview and who does not.